Principal Care Management (PCM) Codes

At Reimagine Care, we believe oncology practices should be empowered with every tool available to improve patient outcomes and practice sustainability. Principal Care Management (PCM) represents a significant opportunity for cancer specialists to be reimbursed for the critical care coordination and patient support they already provide every day. Our Medical Director, Dr. Pallav Mehta, recently authored a byline on this very topic, underscoring its potential to transform oncology care delivery. This guide outlines the latest 2025 PCM codes, reimbursement rates, and oncology-specific applications—helping practices streamline billing, enhance patient engagement, and drive measurable improvements in care.

Principal Care Management (PCM) is a Medicare-reimbursed program designed for patients with a single, high-risk chronic condition that requires ongoing care coordination. Introduced in 2020, PCM enables specialists like oncologists to deliver disease-specific care management services between visits.

PCM codes are part of the broader CPT code family 99421–99429, which encompasses preventive medicine and care management services. Within this range, 99424–99427 are specifically designated for PCM. These are the codes most relevant to oncology practices and the focus of this article.

Key Requirement: Minimum 30 minutes of care management time per calendar month per patient


Official Descriptor (per CPT):
Principal care management services, first 30 minutes of physician or other qualified health care professional time, per calendar month.

  • Physician/QHP personally provides services
  • Disease-specific care plan development
  • 30+ minutes of service time per month
  • Remote patient monitoring integration
  • Care coordination with specialists

Official Descriptor (per CPT):
Each additional 30 minutes of physician or other qualified health care professional time, per calendar month (List separately in addition to code for primary procedure).

  • Ongoing care plan adjustments
  • Reinforcing treatment adherence
  • Additional documentation of services

Official Descriptor (per CPT):
Principal care management services, first 30 minutes of clinical staff time directed by a physician or other qualified health care professional, per calendar month.

  • Clinical staff provides services under supervision
  • RNs, care coordinators, pharmacists eligible
  • “Incident to” physician services
  • Patient symptom monitoring
  • Medication adherence support

Official Descriptor (per CPT):
Each additional 30 minutes of clinical staff time directed by a physician or other qualified health care professional, per calendar month (List separately in addition to code for primary procedure).

  • Additional 30-minute increments by staff
  • Enhanced patient communication
  • Care plan implementation support
  • Treatment adherence monitoring
  • Coordination with care team

PCM is particularly valuable for oncology practices as cancer represents a single, complex chronic condition requiring intensive care coordination. Oncologists can now bill for care management services without needing to identify a second comorbidity (unlike CCM services).

Cancer Care Coordination

  • Chemotherapy regimen monitoring
  • Radiation therapy follow-up
  • Multi-disciplinary team coordination
  • Treatment plan adjustments

Remote Patient Monitoring

  • Symptom tracking between visits
  • Medication adherence monitoring
  • Side effect management
  • Early intervention alerts

Navigation Services

  • Treatment navigation support
  • Resource coordination
  • Social determinants of health
  • Patient advocacy and education

Quality Outcomes

  • Reduced hospitalizations
  • Improved treatment compliance
  • Enhanced patient engagement
  • Better care continuity

Service TypeConditions RequiredTime RequirementProvider TypeKey Focus
PCM1 complex chronic condition30+ minutes/monthPhysician/QHP or Clinical StaffDisease-specific management
CCM2+ chronic conditions20+ minutes/monthPhysician/QHP or Clinical StaffMulti-condition coordination
APCMPrimary care patientsBundle approachPrimary care providers onlyComprehensive primary care

Comprehensive primary care

Generate significant monthly recurring revenue through structured care management billing, with average reimbursements ranging from $48-83 per patient per month.

Quality Metrics

Improve value-based care metrics including patient engagement scores, treatment adherence rates, and reduced emergency department utilization.

Specialty Focus

Enables oncologists and other specialists to provide reimbursed care management for their area of expertise without requiring additional conditions.


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